ea0041gp9 | Adrenal | ECE2016
Williams Tracy A.
, Lenders Jacques W.M.
, Peitzsch Mirko
, Dekkers Tanja
, Dietz Anna S.
, Rump Lars C.
, Willenberg Holger S.
, Treitl Marcus
, Bidlingmaier Martin
, Beuschlein Felix
, Deinum Jaap
, Eisenhofer Graeme
, Reincke Martin
Introduction: Primary aldosteronism (PA) is mainly caused by unilateral aldosterone-producing adenomas (APA) or bilateral adrenal hyperplasia (BAH). Subtype differentiation relies on the invasive and technically challenging adrenal venous sampling (AVS). We recently demonstrated the potential utility of peripheral plasma steroid profiling by LC-MS/MS to distinguish APA and BAH. We tested the following hypotheses: first, if steroid profiling in combination with AVS, effectively...